Robert A. Clark, Chairman, MD
Professor of Medicine, University of Texas, San Antonio
Dr. Robert A. Clark is Professor of Medicine, University of Texas, San Antonio. Robert leads an active basic science and translational research program with a focus on mechanisms of the inflammatory response and the cell biology and biochemistry of human phagocytic cells. His group has made seminal contributions to the fundamental understanding of the generation of reactive oxygen species by the phagocyte NADPH oxidase system and the genetics and biochemistry of NADPH oxidase deficiency in the inherited disorder chronic granulomatous disease. In recent years he has turned his attention to the structure, function, and physiologic role of the non-myeloid members of the NOX gene family and to the role of reactive oxygen species in aging and neurodegeneration.
Karl-Heinz Krause, MD
Professor of Medicine, Faculty of Medicine & University Hospitals of Geneva
Dr. Karl-Heinz Krause is Professor of Medicine at the Faculty of Medicine & University Hospitals of Geneva, as well as honorary professor at the Bejing Hospital, China. He received his MD from the Ludwig-Maximilian University (Munich) in 1982. From 1982 to 1989, he received clinical training in internal medicine and infectious diseases at the Universities of Munich, Geneva and Iowa. Starting in 1984, Karl-Heinz has been actively involved in inflammation research. Since 1998, he focused his research further on mechanisms of aging and treatment of age-associated diseases, particularly on the NOX family of NADPH oxidases as a pathophysiologically important source of oxygen radicals. He is an elected member of the Swiss Academy of Medical Sciences and the American Society for Clinical Investigation.
Dave Lambeth, MD, PhD
Professor of Pathology, Emory University Medical School, Atlanta
Dr. David Lambeth is Professor of Pathology and Laboratory Medicine, and of Biochemistry at Emory University (Atlanta) and is founder of Theros Pharmaceuticals, Inc. He received his MD and PhD degrees from Duke University. After moving to Emory in 1980, his laboratory developed an interest in the enzymology of reactive oxygen generation in neutrophils. His lab has contributed extensively to the understanding the phagocyte NADPH oxidase and its regulation by protein-protein interactions. As a result of his interests in the origin of reactive oxygen generation in non-phagocytic cells, his laboratory reported the first homolog of the phagocyte oxidase, Nox1, in 1999. His laboratory has subsequently contributed extensively to the identification of novel NOX isoforms and their enzymatic and regulatory mechanisms.
Chihiro Yabe-Nishimura, MD, PhD
Professor of Pharmacology, Kyoto Prefectural University of Medicine
Dr. Chihiro Yabe-Nishimura is Professor of Pharmacology at Kyoto Prefectural University of Medicine. Further to conducting research projects in the field of diabetes, since 2000 she has focused on the the novel NOX family of NADPH oxidases. Chihiro is Councillor of the Japanese Pharmacological Society, the Japan Diabetes Society, and the Japanese Society of Clinical Pharmacology and Therapeutics.